Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CROCETIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CROCETIN |
| Key Genes/Proteins | amyloid-β |
graph TD
CROCETIN[CROCETIN]
CROCETIN -->|suppresses| Reactive_Oxygen_Species[Reactive Oxygen Species]
CROCETIN -->|inhibits| Neuroinflammation[Neuroinflammation]
CROCETIN -->|activates| STK11[STK11]
CROCETIN -->|upregulates| BDNF[BDNF]
CROCETIN -->|modulates| PI3K_AKT[PI3K/AKT]
CROCETIN -->|promotes clearance of| amyloid__[amyloid-β]
CROCETIN -.protects against.-> Gut_Microbiota_Dysbiosis[Gut Microbiota Dysbiosis]
CROCETIN -->|treats| Cognitive_Dysfunction[Cognitive Dysfunction]
CROCETIN -->|promotes| AUTOPHAGY[AUTOPHAGY]| Target | Relation | Type | Str |
|---|---|---|---|
| Autophagy | associated_with | process | 0.95 |
| Amyloid-β Clearance | associated_with | process | 0.95 |
| Neuroinflammation | inhibits | process | 0.90 |
| Reactive Oxygen Species | suppresses | process | 0.90 |
| PI3K/AKT | modulates | pathway | 0.85 |
| Mitochondrial Function | associated_with | process | 0.85 |
| STK11 | activates | gene | 0.85 |
| BDNF | upregulates | protein | 0.85 |
| Insulin Sensitivity | associated_with | phenotype | 0.85 |
| amyloid-β | promotes clearance of | protein | 0.80 |
| Gut Microbiota Dysbiosis | protects_against | process | 0.80 |
| Blood-Brain Barrier Integrity | associated_with | process | 0.80 |
| Cognitive Dysfunction | treats | phenotype | 0.75 |
| AUTOPHAGY | promotes | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CROCETIN in their description or question text
No additional research found