gene

CHD7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CHD7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

7Connections

0Hypotheses

0Analyses

4Outgoing

3Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	CHD7
Full Name	Chromodomain Helicase DNA Binding Protein 7
Chromosome	8q12.2
Function	encodes a large ATP-dependent chromatin remodeling factor essential for embryonic development, particularly of the neural crest, inner ear, and reproductive system.
Molecular Weight	220 kDa
Amino Acids	2000 aa
UniProt ID	Q9Y5J1
NCBI Gene ID	55636
Ensembl ID	ENSG00000171316
OMIM	608992
GeneCards	CHD7
Human Protein Atlas	CHD7
Associated Diseases	neurodegeneration
KG Connections	7 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CHD7 — AlphaFold Q9Y5J1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CHD7 — Chromodomain Helicase DNA Binding Protein 7

gene · 1651 words

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Pathway Diagram

graph TD
    CHD7["CHD7"]
    Cancer{"Cancer"}
    CHD7 -->|"therapeutic target"| Cancer
    Tumor{"Tumor"}
    CHD7 -->|"activates"| Tumor
    RB1["RB1"]
    CHD7 -->|"therapeutic target"| RB1
    neurodegeneration["neurodegeneration"]
    CHD7 -->|"implicated in"| neurodegeneration
    RB1 -->|"therapeutic target"| CHD7
    PTEN["PTEN"]
    PTEN -->|"associated with"| CHD7
    CANCER["CANCER"]
    CANCER -->|"therapeutic target"| CHD7
    style CHD7 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (4)

Target	Relation	Type	Str
PTEN	coexpressed_with	gene	0.80
Cancer	therapeutic_target	disease	0.65
Tumor	activates	disease	0.65
RB1	therapeutic_target	gene	0.60

Incoming (3)

Source	Relation	Type	Str
CANCER	therapeutic_target	gene	0.60
RB1	therapeutic_target	gene	0.60
PTEN	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CHD7 in their description or question text

No additional research found