Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CD300F: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| TREM2 | associated_with | protein | 0.60 |
| inflammaging | regulates | biological_process | 0.60 |
| inflammaging | inhibits | pathway | 0.50 |
| neurodegeneration | associated_with | disease | 0.50 |
| GAL3ST1 | co_associated_with | gene | 0.40 |
| TREM2 | co_associated_with | gene | 0.40 |
| CDKN2A | co_associated_with | gene | 0.40 |
| CXCL10 | co_associated_with | gene | 0.40 |
| STING1 | co_associated_with | gene | 0.40 |
| Source | Relation | Type | Str |
|---|---|---|---|
| h-7857b01b | targets | hypothesis | 0.30 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| CD300f Immune Checkpoint Activation | 0.545 | neurodegeneration | Gene expression changes in aging mouse b |
| CD300f Immunoglobulin Receptor as Neuroinflammatory Brake | 0.105 | neurodegeneration | Neuroinflammation Biomarker Panel for Ea |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 44 hypotheses Top: 0.990
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Microglia at the Forefront: New Insights From the Glial Club South Cone Meeting [PMID:41668347] | Giambartolomei GH, Iribarren P, Pasquini | J Neurochem | 2026 | 0 |
| Corrigendum to “CD300f enables microglial damage sensing, efferocytosis, and apo [PMID:41734445] | Negro-Demontel Luciana; Evans Frances; C | Brain, Behavior, and Immunity | 2026 | 0 |
| IgE-dependent anaphylaxis is regulated by sphingolipid binding to activating and [PMID:41790557] | Izawa K, Kaitani A, Enomoto Y, Ando T, Y | Cell Rep | 2026 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning CD300F in their description or question text
No additional research found