entity

Brain Insulin Resistance

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Brain Insulin Resistance: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

11Connections
1Hypotheses
0Analyses
4Outgoing
7Incoming
0Experiments
0Debates

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Outgoing (4)

TargetRelationTypeStr
Neurodegenerationassociated_withprocess0.85
Neuroinflammationassociated_withprocess0.80
Alzheimer'S Diseasecontributes_todisease0.60
Cognitive Declinecontributes_tophenotype0.50

Incoming (7)

SourceRelationTypeStr
Intranasal Insulintargetsdrug0.70
PI3Kregulatesgene0.70
AKTinhibitsgene0.70
PI3K/Aktdisruptsgene0.70
AKTassociated_withgene0.60

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Brain Insulin Resistance with Glucose Transporter Dysfunctio 0.596 neurodegeneration Metabolic reprogramming in neurodegenera

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (9)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
Comparative study of the glucolipid profile and GLUTs gene expression in respons [PMID:41232212] ["Wang Z", "Wang H", "Du P", "Zhang X", Poultry science 2025 0
Altered Glut4, IRAP, and Brain Insulin Signaling in a Mouse Model of Epilepsy an [PMID:41369048] ["Xu W", "Neal E", "Barlow N", "Thompson Journal of neurochemistry 2025 0
Targeting glucose transporters in parkinson's disease: a novel metabolic approac [PMID:40879857] ["Singh G", "Ansari S", "Aran K"] Metabolic brain disease 2025 0
Tirzepatide prevents neurodegeneration through multiple molecular pathways. [PMID:38287296] Fontanella RA, Ghosh P, Pesapane A, Takt Journal of translational medic 2024 0
A high fat diet potentiates neonatal iron overload-induced memory impairments in [PMID:38358514] ["do Nascimento F", "de Freitas B", "Dos European journal of nutrition 2024 0
[WALANT - Wide Awake Local Anaesthesia No Tourniquet: Complications in elective [PMID:35168268] Wieschollek S, Forster S, Megerle K Handchirurgie, Mikrochirurgie, 2022 0
Complete Genome Sequence of Geobacter sp. Strain FeAm09, a Moderately Acidophili [PMID:33446582] Yadav P, Antony-Babu S, Hayes E, Healy O Microbiology resource announce 2021 0
Engineering complex communities by directed evolution. [PMID:33986540] Chang CY, Vila JCC, Bender M, Li R, Mank Nature ecology & evolution 2021 0
Successful Nonoperative Treatment of Osteochondritis Dissecans of the Humeral Ca [PMID:34825100] Tajika T, Kuboi T, Endo F, Hatori Y, Sai Progress in rehabilitation med 2021 0

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning Brain Insulin Resistance in their description or question text

No additional research found