gene

atp1b3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about atp1b3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections

0Hypotheses

0Analyses

2Outgoing

4Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	ATP1B3
Chromosome	3q23
Protein Type	Enzyme
Function	Critical for maintaining the endocochlear potential
Subcellular Localization	**: Primar
Amino Acids	279 aa
Ensembl ID	ENSG00000069899
GeneCards	ATP1B3
Human Protein Atlas	ATP1B3
ATP1B1	Ubiquitous, major isoform in most tissues
ATP1B2	Primarily neuronal
ATP1B3	Enriched in brain, heart, and specialized epithelial cells
ATP1B4	Primarily testis
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

atp1b3

gene · 1714 words

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Pathway Diagram

flowchart TD
    ATP1B3["ATP1B3"] -->|"interacts with"| ABCB1["ABCB1"]
    ATP1B3["ATP1B3"] -->|"implicated in"| neurodegeneration["neurodegeneration"]
    IREB2["IREB2"] -->|"interacts with"| ATP1B3["ATP1B3"]
    DNAJA1["DNAJA1"] -->|"interacts with"| ATP1B3["ATP1B3"]
    ATP1B1["ATP1B1"] -->|"interacts with"| ATP1B3["ATP1B3"]
    style ATP1B3 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style ABCB1 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style neurodegeneration fill:#006494,stroke:#333,color:#e0e0e0
    style IREB2 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style DNAJA1 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style ATP1B1 fill:#4a1a6b,stroke:#333,color:#e0e0e0

Outgoing (2)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ATP1B3	data_in	dataset_row	0.00
ABCB1	interacts_with	gene	0.60

Incoming (4)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ATP1B3	data_in	dataset_row	0.00
IREB2	interacts_with	gene	0.60
DNAJA1	interacts_with	gene	0.60
ATP1B1	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning atp1b3 in their description or question text

No additional research found