concept

ASC1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ASC1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

18Connections

0Hypotheses

0Analyses

12Outgoing

6Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ASC1
Key Genes/Proteins	ERα, ESR1, P300, SRC1, UFM1, UFSP2
Related Diseases	breast cancer, Breast Cancer, Tumor Formation

Pathway Diagram

graph TD
    ASC1[ASC1]
    ASC1 -->|mediates| Estrogen_Receptor_Alpha_Transa[Estrogen Receptor Alpha Transactivation]
    ASC1 -->|interacts| ER_[ERΑ]
    ASC1 -->|modified_by| UFM1[UFM1]
    ASC1 -->|implicated in| breast_cancer[breast cancer]
    ASC1 -->|interacts| ESR1[ESR1]
    ASC1 -->|promotes| Breast_Cancer[Breast Cancer]
    ASC1 -->|interacts| P300[P300]
    ASC1 -->|interacts| SRC1[SRC1]
    UFM1 -->|modulates| ASC1
    UFSP2[UFSP2] -->|interacts| ASC1
    ESR1 -->|activates| ASC1

Outgoing (12)

Target	Relation	Type	Str
Estrogen Receptor Alpha Transactivation	mediates	process	0.95
ERΑ	interacts_with	receptor	0.90
breast cancer	implicated_in	disease	0.90
UFM1	associated_with	protein	0.90
ERα	transactivation_is_crucial_for	protein	0.90
Breast Cancer	promotes	disease	0.90
ESR1	interacts_with	protein	0.90
Tumor Formation	associated_with	phenotype	0.85
P300	interacts_with	protein	0.80
SRC1	interacts_with	protein	0.80
ESR1	therapeutic_target	protein	0.80
UFM1	activates	gene	0.60

Incoming (6)

Source	Relation	Type	Str
UFM1	modulates	protein	0.95
UFM1	modifies	protein	0.90
UFSP2	interacts_with	enzyme	0.85
ESR1	activates	protein	0.85
UFSP2	inhibits	protein	0.85
UFSP2	cleaves	enzyme	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ASC1 in their description or question text

No additional research found