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OPA1 — Optic Atrophy 1

wiki page Created: 2026-04-02T20:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-opa1
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OPA1
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📊 Evidence Profile
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
24
Outgoing
32
0 supporting 0 contradicting 0 neutral
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Linked Artifacts (56)
see_also📖TWNK Gene60%
see_also📖Apoptosis Pathway in Neurodegeneration60%
see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%
see_also📖TIMM50 Gene - Mitochondrial Import Protein60%
see_also📖SLC25A4 Gene60%
see_also📖SUMO1 — Small Ubiquitin-Like Modifier 160%
see_also📖TYMP Gene60%
see_also📖polg260%
see_also📖Apoptosis in Neurodegeneration60%
see_also📖SUCLA2 Gene60%
see_also📖YME1L1 Gene60%
see_also📖Alzheimer Indonesia60%
see_also📖RNASEH1 — Ribonuclease H160%
see_also📖DGUOK — Deoxyguanosine Kinase60%
see_also📖AKT1 Gene60%
see_also📖RRM2B Gene60%
see_also📖AMPK (AMP-Activated Protein Kinase)60%
see_also📖Cerebellum60%
see_also📖timm2260%
see_also📖SENP1 — SUMO Specific Peptidase 160%
see_also📖Packard Center for ALS Research60%
see_also📖TK2 Gene60%
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mentions🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration50%
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mentions🧪Extracellular Matrix Stiffness Modulation50%
mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%
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related🧪APOE-Dependent Autophagy Restoration50%
mentions🧪Digital Twin-Guided Metabolic Reprogramming50%
mentions🧪Microglia-Derived Extracellular Vesicle Engineering for Targ50%
related🔬Investigate prion-like spreading of tau pathology through co50%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Digital Twin-Guided Metabolic Reprogramming40%
related🧪HSP90-Tau Disaggregation Complex Enhancement40%
related🧪TFAM overexpression creates mitochondrial donor-recipient gr40%
mentions🔬What are the mechanisms underlying mitochondrial transfer be35%
mentions🔬Investigate prion-like spreading of tau pathology through co35%
mentions🔬What are the mechanisms underlying mitochondrial transfer be35%
mentions🔬What are the mechanisms underlying digital biomarkers and ai35%

💬 Discussion