| Gene Symbol | VGAT |
| Aliases | VGATPROTEIN |
| Function | VGAT (SLC32A1), also known as VIAAT (Vesicular Inhibitory Amino Acid Transporter), is a 525-amino acid transmembrane protein that packages GABA and glycine into synaptic vesicles. |
| Subcellular Localization | Synaptic vesicles of GABAergic and glycinergic neurons ; Pr |
| Molecular Weight | 57 kDa |
| Amino Acids | 525 aa |
| Pathways | GABAergic signaling |
| GeneCards | VGAT |
| Human Protein Atlas | VGAT |
| 10 transmembrane domains | Characteristic of the SLC family |
| Vesicular lumen orientation | Transports inhibitory amino acids into vesicles |
| Proton gradient coupling | Uses V-ATPase-generated H+ gradient |
| Functional homodimer | Forms functional dimers for transport |
| GABA packaging | Packages GABA into synaptic vesicles [1] |
| Glycine packaging | Also transports glycine in spinal cord and brainstem [1] |
| Interactions | GABA, VACHT, VGLUT1 |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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