| Gene Symbol | TLR3 |
| Full Name | Toll-Like Receptor 3 |
| Chromosome | 4q35 |
| Protein Type | Receptor |
| Function | TLR3 is expressed in microglia, astrocytes, neurons, and oligodendrocytes. |
| Primary Expression | various cell types in the brain and plays a critical role in antiviral immune responses and has been implicated in neurodegenerative diseases |
| Amino Acids | 904 aa |
| Pathways | NF-κB, MAPK pathway |
| UniProt ID | Q9Y5Y9 |
| NCBI Gene ID | 7098 |
| Ensembl ID | ENSG00000164342 |
| OMIM | 603029 |
| GeneCards | TLR3 |
| Human Protein Atlas | TLR3 |
| Extracellular domain | Leucine-rich repeat (LRR) motifs responsible for ligand recognition |
| Associated Diseases | Ms |
| Interactions | ADAR1, AGING, AND, APOPTOSIS, CANCER, CGAS |
| KG Connections | 170 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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