| Gene Symbol | TAC1PROTEIN |
| Chromosome | 7q21 |
| Function | The tachykinin system represents one of the oldest neuropeptide signaling systems in evolution, with conserved functions across species from amphibians to humans. |
| Primary Expression | distinct neuronal populations within the basal ganglia, cortex, hippocampus, and brainstem, where they modulate dopaminergic signaling, GABAergic tran |
| Molecular Weight | 17 kDa |
| Amino Acids | 11 aa |
| GeneCards | TAC1PROTEIN |
| Human Protein Atlas | TAC1PROTEIN |
| Preprotachykinin-A (PPT-A) | Generates Substance P (SP, 11 amino acids), Neurokinin A (NKA, 10 amino acids), neuropeptide K (NPK, 36 amino acids), and neuropeptide γ (NPγ, 21 amino acids) |
| Preprotachykinin-B (PPT-B) | Generates Neurokinin B (NKB, 10 amino acids), encoded by the separate **TAC3 gene** |
| Associated Diseases | neurodegeneration |
| Interactions | TRPM8, WNT3A |
| KG Connections | 27 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!