| Gene Symbol | SSBP1 |
| Aliases | SSBP1PROTEIN |
| Chromosome | 14q12 |
| Protein Family | SSB-like protein family |
| Function | encodes a mitochondrial single-stranded DNA-binding protein essential for mitochondrial DNA (mtDNA) maintenance, replication, and repair. |
| Molecular Weight | 17 kDa |
| Amino Acids | 172 aa |
| Pathways | Apoptosis, Mitochondrial Function |
| UniProt ID | P04802 |
| GeneCards | SSBP1 |
| Human Protein Atlas | SSBP1 |
| Gene | SSBP1 |
| Structure | Homotrimer with OB-fold domains |
| Mitochondrial Dysfunction | Impaired mtDNA replication leads to mitochondrial dysfunction, reducing neuronal energy production and increasing oxidative stress - both hallmarks of AD pathology. |
| Associated Diseases | Als, Alzheimer, Cancer, Glioblastoma, Ms |
| Interactions | ALZHEIMER, AND, APOE, APOPTOSIS, APP, CALB1 |
| KG Connections | 102 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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