protein 576 words KG: RIGIPROTEIN
Contents

RIG-I Protein

🔬 Protein Info
Gene SymbolRIG
Full NameI Protein
AliasesRIGIPROTEIN
FunctionRig I Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Subcellular Localizationto Cytoplasm and plays a significant role in the pathogenesis of [Alzheimer's Di
GeneCardsRIG
Human Protein AtlasRIG
PAMP recognitionBinds 5' triphosphate double-stranded RNA (5'PPP dsRNA)
Short dsRNA detectionRecognizes short viral dsRNA
Signal transductionActivates MAVS (mitochondrial antiviral signaling protein)
Type I IFN inductionTriggers production of interferon-alpha/beta
C-terminal domain (CTD)RNA binding and 5'PPP recognition
Helicase domainATP-dependent RNA unwinding
N-terminal CARD domainsSignal transduction via MAVS
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (12)

Phase-Separated Organelle Targeting
Score: 0.73
Smartphone-Detected Motor Variability Correction
Score: 0.74
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69
Ganglioside Rebalancing Therapy
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Sphingolipid Metabolism Reprogramming
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62
Netrin-1 Gradient Restoration
Score: 0.59
Vocal Cord Neuroplasticity Stimulation
Score: 0.52

Related Analyses (9)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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