| Gene Symbol | POLE |
| Full Name | DNA Polymerase Epsilon |
| Chromosome | 12q24.3 |
| Function | is a gene located on chromosome 12q24. |
| Primary Expression | Hippocampus, Cerebral cortex, Cerebellum, Substantia nigra |
| Subcellular Localization | </strong></td><td>Nucleus (chromatin)</td></tr> |
| Molecular Weight | 261 kDa |
| Amino Acids | 2308 aa |
| Pathways | Apoptosis, Blood-Brain Barrier, Er Stress, Ferroptosis, Inflammasome |
| UniProt ID | Q07864 |
| NCBI Gene ID | 5426 |
| Ensembl ID | ENSG00000177042 |
| OMIM | 174762 |
| GeneCards | POLE |
| Human Protein Atlas | POLE |
| Associated Diseases | Aging, Anxiety, Cancer, Depression, Epilepsy, Neurodegeneration |
| Interactions | Actin, AND, APOPTOSIS, ASTROCYTE, ATP, BAX |
| KG Connections | 242 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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