protein 2,374 words KG: NOTCH2PROTEIN
Contents

Notch2 Protein

🔬 Protein Info
Gene SymbolNOTCH2
Full NameNotch Receptor 2
Chromosome1p11
Protein TypeReceptor
Functionencodes a highly conserved transmembrane protein that serves as a critical regulator of cell fate decisions, tissue homeostasis, and developmental processes throughout the nervous and vascular syst...
Primary ExpressionCerebral cortex, Hippocampus, Vascular smooth muscle
Subcellular Localization</strong></td><td>Cell membrane, Nucleus</td></tr>
Molecular Weight265 kDa
PathwaysPathway: An Overview, NOTCH, Notch, Notch Signaling
UniProt IDQ12983
NCBI Gene ID4853
Ensembl IDENSG00000134250
OMIM600275
GeneCardsNOTCH2
Human Protein AtlasNOTCH2
Associated DiseasesDiabetes, Glioblastoma
InteractionsABCA1, AQP4, CANCER, CCL2, CDKN2A, DLL4
KG Connections192 knowledge graph edges
DatabasesGeneCardsHPASTRING

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