protein 544 words KG: NLRC3PROTEIN
Contents

NLRC3 Protein

🔬 Protein Info
Gene SymbolNLRC3
Full NameNLR Family CARD Domain Containing 3
Chromosome16p13.3
Protein TypeReceptor
Functionis a member of the NOD-like receptor (NLR) family of proteins.
Primary Expressionvarious tissues, with highest expression in immune cells and epithelial tissues
Subcellular Localization</strong></td><td>Cytoplasm</td></tr>
Molecular Weight85 kDa
Amino Acids755 aa
Exons14
PathwaysNf-Κb
UniProt IDQ7RTV0
NCBI Gene ID81128
Ensembl IDENSG00000167900
OMIM611362
GeneCardsNLRC3
Human Protein AtlasNLRC3
Associated DiseasesMs
InteractionsAMPK, APOPTOSIS, INFLAMMATION, MLCK, NLRP3, STAT3
KG Connections21 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (5)

SASP-Mediated Complement Cascade Amplification
Score: 0.91
Microbial Inflammasome Priming Prevention
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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