| Gene Symbol | MOG |
| Full Name | Myelin Oligodendrocyte Glycoprotein |
| Aliases | MOGPROTEIN |
| Chromosome | 6p22.2 |
| Function | MOG is a type I transmembrane glycoprotein with an immunoglobulin-like domain. |
| Molecular Weight | 28 kDa |
| Pathways | Complement, Oxidative Phosphorylation |
| NCBI Gene ID | 4340 |
| Ensembl ID | ENSG00000137355 |
| GeneCards | MOG |
| Human Protein Atlas | MOG |
| Extracellular domain | Single Ig-like V-type domain ( residues 1-124) containing the immunodominant epitope |
| Transmembrane domain | Single α-helical segment (residues 125-147) |
| Cytoplasmic tail | Short cytoplasmic domain (residues 148-218) with signaling motifs |
| Glycosylation | N-linked glycosylation at Asn47 affects antigenicity |
| Associated Diseases | AD, Aging, Als, Autoimmune, MOGAD |
| Known Drugs/Compounds | metformin |
| Interactions | AMPK, APOPTOSIS, AQP4, ATG5, ATP, AXON |
| SciDEX Hypotheses | Oligodendrocyte White Matter Vulnerability |
| KG Connections | 275 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
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