protein 1,014 words KG: GP130PROTEIN
Contents

gp130 Protein - IL-6 Signal Transducer

🔬 Protein Info
Gene SymbolGP130PROTEIN
Full Namegp130 - IL-6 Signal Transducer
Protein TypeProtein
Functionis a common signal-transducing receptor subunit used by multiple interleukin-6 family cytokines.
Subcellular LocalizationCell membrane, cytoplasm (after ligand binding) ; Protein Family : IL-6 rece
Molecular Weight130 kDa
Amino Acids917 aa
UniProt IDSearch UniProt
GeneCardsGP130PROTEIN
Human Protein AtlasGP130PROTEIN
Common receptor subunitShared by 10+ cytokine receptors
Signal transducerEssential for downstream signaling
Expression patternUbiquitous with high expression in brain
IsoformsMultiple splice variants exist
Associated DiseasesALS
Known Drugs/CompoundssIL-11R and sIL-6R
InteractionsIL6, JAK1, STAT3
KG Connections8 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.