protein 638 words KG: FLT3PROTEIN
Contents

FLT3 Protein

🔬 Protein Info
Gene SymbolFLT3
AliasesFLT3PROTEIN
Molecular Weight143 kDa
PathwaysPI3K, MAPK
GeneCardsFLT3
Human Protein AtlasFLT3
Extracellular domain5 immunoglobulin-like domains for ligand binding
Transmembrane helixSingle pass through the membrane
Juxtamembrane domainContains regulatory motifs
Kinase domainIntracellular tyrosine kinase activity
C-terminal tailContains tyrosine residues for signaling
MicrogliaPrimary immune cells of the brain
NeuronsDevelopmental expression, lower in adults
Neural progenitor cellsDuring neurogenesis
Endothelial cellsBlood-brain barrier component
InteractionsABL1, ABL2, App, ATF6, CP, CR1
KG Connections71 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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