| Gene Symbol | CHD4 |
| Full Name | Chromodomain Helicase DNA Binding Protein 4 |
| Chromosome | 12p12.3 |
| Function | CHD4 encodes a member of the chromodomain helicase family (CHD) that functions as an ATP-dependent chromatin remodeler. |
| Primary Expression | the central nervous system: |
| Subcellular Localization | ** | Nucleus (chromatin-associated) | |
| Molecular Weight | 226 kDa |
| UniProt ID | Q14839 |
| NCBI Gene ID | 2298 |
| Ensembl ID | ENSG00000124177 |
| OMIM | 605602 |
| GeneCards | CHD4 |
| Human Protein Atlas | CHD4 |
| Chromodomains (CD1, CD2) | Two tandem chromodomains that bind H3K9me3 and H3K27me3 |
| SNF2-type ATPase domain | Central helicase domain that hydrolyzes ATP for chromatin remodeling |
| Associated Diseases | ALS, Migraine |
| Interactions | CHIP, KDM5A |
| KG Connections | 37 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!