protein 1,592 words KG: C2PROTEIN
Contents

C2 Protein

🔬 Protein Info
Gene SymbolC2
Full NameComplement Component 2
Chromosome6p21.3
Functionencodes a 732-amino acid zymogen that, upon activation, generates the C3 convertase complex essential for complement cascade amplification.
Molecular Weight83 kDa
Amino Acids732 aa
Exons18
UniProt IDP06610
NCBI Gene ID717
Ensembl IDENSG00000166278
OMIM120490
GeneCardsC2
Human Protein AtlasC2
Von Willebrand factor type A domainInvolved in binding to other complement components and cell surfaces
Serine protease domainThe catalytic domain that becomes active upon cleavage
Associated Diseasesautism spectrum disorder
InteractionsMAVS, PI3KC3, SIRT2
KG Connections17 knowledge graph edges
DatabasesGeneCardsHPASTRING

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