| Gene Symbol | 3RTAU |
| Chromosome | 17q21 |
| Subcellular Localization | ** | Axons, neuronal soma | |
| Molecular Weight | 68 kDa |
| Amino Acids | 381 aa |
| Repeat domain structure | Contains R1, R3, and R4 repeats (lacks R2) |
| Microtubule-binding regions | Three hexapeptide motifs (^275KVQIINKK^280, ^306VQIVYKPVDLSKVTSKC^322) |
| N-terminal inserts | Can have 0, 1, or 2 N-terminal inserts (0N, 1N, 2N isoforms) |
| Total length | 352-381 amino acids depending on N-terminal splicing |
| Proline-rich domain | Projecting N-terminal region that modulates interactions |
| Repeat domain | Core microtubule-binding region |
| C-terminal region | Involved in filament formation |
| Phosphorylation sites | Multiple serine, threonine, and tyrosine residues |
| Microtubule assembly | Promotes tubulin polymerization into microtubules |
| Axonal transport | Supports bidirectional transport via motor proteins (kinesins, dyneins) |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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