| Gene Symbol | PDHX |
| Full Name | Pyruvate Dehydrogenase Complex Component X |
| Chromosome | 11p13 |
| Protein Type | Dehydrogenase |
| Function | E1 (Pyruvate Dehydrogenase): Heterotetramer of PDHA1 (α2β2) that decarboxylates pyruvate |
| Primary Expression | Ubiquitous; highest in heart, brain, liver, and skeletal muscle |
| Molecular Weight | 54 kDa |
| Amino Acids | 501 aa |
| UniProt ID | [Q9BRU2](https://www.uniprot.org/uniprot/Q9BRU2) |
| Ensembl ID | ENSG00000165478 |
| GeneCards | PDHX |
| Human Protein Atlas | PDHX |
| Structural scaffolding | Provides the binding platform for E3 attachment |
| Catalytic facilitation | Enables efficient transfer of reducing equivalents |
| Complex stability | Maintains structural integrity of the entire PDC |
| Associated Diseases | Als |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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