Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NDNF: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NDNF |
| Key Genes/Proteins | DDX1, SLCO1C1, SOD1, TGM2 |
| Related Diseases | Amyotrophic lateral sclerosis, Amyotrophic Lateral Sclerosis |
graph TD
NDNF[NDNF]
NDNF -->|treats| Amyotrophic_Lateral_Sclerosis[Amyotrophic Lateral Sclerosis]
NDNF -->|expressed in| Motor_Neuron[Motor Neuron]
NDNF -.protects against.-> Amyotrophic_lateral_sclerosis[Amyotrophic lateral sclerosis]
NDNF -->|interacts| SLCO1C1[SLCO1C1]
NDNF -->|targets| TGM2[TGM2]
NDNF -->|regulates| SOD1[SOD1]
NDNF -->|expressed in| neurons[neurons]
NDNF -->|data_in| benchmark_ot_ad_answer_key_NDN[benchmark_ot_ad_answer_key:NDNF]
AAV[AAV] -->|targets| NDNF
DDX1[DDX1] -->|targets| NDNF
benchmark_ot_ad_answer_key_NDN -->|data_in| NDNF| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:NDNF | data_in | dataset_row | 0.00 |
| Amyotrophic Lateral Sclerosis | treats | disease | 0.85 |
| Amyotrophic lateral sclerosis | protects_against | disease | 0.80 |
| Motor Neuron | expressed_in | cell_type | 0.80 |
| SOD1 | regulates | gene | 0.60 |
| SLCO1C1 | interacts_with | gene | 0.60 |
| SLCO1C1 | targets | gene | 0.60 |
| TGM2 | targets | gene | 0.60 |
| SLCO1C1 | associated_with | gene | 0.60 |
| neurons | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:NDNF | data_in | dataset_row | 0.00 |
| AAV | targets | drug | 0.90 |
| DDX1 | targets | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NDNF in their description or question text
No additional research found