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Institution: RA Capital Management
institution
1,417 words
KG: RA
Contents
RA Capital Management
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Knowledge Graph
Related Hypotheses (11)
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
APOE-TREM2 Interaction Modulation
Score: 0.74
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
TREM2-Dependent Microglial Senescence Transition
Score: 0.54
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
TREM2-mediated microglial tau clearance enhancement
Score: 0.59
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
LRP1-Dependent Tau Uptake Disruption
Score: 0.58
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
Extracellular Vesicle Biogenesis Modulation
Score: 0.56
Related Analyses (5)
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Related Experiments (1)
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Knowledge Graph (12 edges)
SLC16A2
implicated_in
RA
SLC16A1
implicated_in
RA
GSS
implicated_in
RA
CYP2E1
implicated_in
RA
IDH2
implicated_in
RA
IDH1
implicated_in
RA
RBP
associated_with
RA
MAP1B
implicated_in
RA
MAP2
implicated_in
RA
MAP6
implicated_in
RA
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