| Gene Symbol | UROCORTIN |
| Chromosome | 2p23.3 |
| Function | encodes a 40-amino acid neuropeptide belonging to the corticotropin-releasing hormone (CRH) family. |
| Primary Expression | pituitary, cortex, and cerebellum |
| Molecular Weight | 4.7 kDa |
| Amino Acids | 40 aa |
| Pathways | Blood-Brain Barrier, Neuroprotection |
| UniProt ID | [Q9UBP3](https://www.uniprot.org/uniprot/Q9UBP3) |
| Ensembl ID | ENSG00000163794 |
| GeneCards | UROCORTIN |
| Human Protein Atlas | UROCORTIN |
| Hypothalamus | Highest expression in the paraventricular nucleus (PVN), where it co-localizes with CRH neurons |
| Amygdala | Abundant in the central nucleus, involved in emotional processing |
| Hippocampus | Expression in CA1-CA3 regions and dentate gyrus[@bayatti2003] |
| Cortex | Moderate expression throughout cortical layers |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| Interactions | CRH, CRHR1, Leptin |
| KG Connections | 26 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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