| Gene Symbol | SPG15 |
| Full Name | Spastic Paraplegia 15 |
| Chromosome | 14q24.3. |
| Protein Type | Gene |
| Function | is a hereditary neurological disorder classified as a complex form of hereditary spastic paraplegia (HSP) characterized by progressive lower limb spasticity and weakness. |
| Molecular Weight | 209 kDa |
| Amino Acids | 897 aa |
| Exons | 47 |
| GeneCards | SPG15 |
| Human Protein Atlas | SPG15 |
| Zinc Finger Domains | Multiple C2H2-type zinc finger motifs are present throughout the protein, suggesting roles in DNA binding or protein-protein interactions. |
| Proline-Rich Region | The central region contains proline-rich sequences that may serve as interaction sites for SH3 domain-containing proteins involved in signaling pathways. |
| Associated Diseases | neurodegeneration |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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