gene 1,338 words KG: RPA3
Contents

RPA3

🧬 Gene Info
Gene SymbolRPA3
Full NameReplication Protein A3
Chromosome7q32.3
Functionis a subunit of the heterotrimeric Replication Protein A complex (RPA), the major single-stranded DNA (ssDNA)-binding protein in eukaryotic cells.
Molecular Weight70 kDa
UniProt ID[P35274](https://www.uniprot.org/uniprot/P35274)
Ensembl IDENSG00000186871
GeneCardsRPA3
Human Protein AtlasRPA3
RPA1 (RPA70)70 kDa subunit - contains multiple DNA-binding domains (DBDs) and protein interaction domains
RPA2 (RPA32)32 kDa subunit - phosphorylated in response to DNA damage, regulates protein interactions
RPA3 (RPA14)14 kDa subunit - smallest subunit, essential for complex assembly and stability
Associated DiseasesCancer, Glioblastoma, Ms, Tumor
KG Connections8 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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