| Gene Symbol | PROS1 |
| Full Name | Protein S (Vitamin K-Dependent Protein S) |
| Chromosome | 3q11.2 |
| Function | encodes a vitamin K-dependent plasma protein that plays essential roles in both coagulation regulation and cellular signaling[@dahlback2007]. |
| Primary Expression | excitatory and inhibitory neurons throughout the brain, with particularly high levels in the hippocampus and cerebral cortex |
| Molecular Weight | 70 kDa |
| Amino Acids | 676 aa |
| Exons | 15 |
| GeneCards | PROS1 |
| Human Protein Atlas | PROS1 |
| Gla domain | N-terminal γ-carboxylated glutamate residues that mediate calcium-dependent membrane binding |
| Thrombospondin type I repeats (TSR) | Multiple repeats that mediate protein-protein interactions |
| C-terminal lectin-like domain | Mediates interaction with TAM receptors |
| Associated Diseases | Alzheimer's disease |
| Interactions | AXL |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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