| Gene Symbol | MAPK11 |
| Full Name | Mitogen-Activated Protein Kinase 11 |
| Aliases | Mitogen-activated protein kinase 11 (p38β) |
| Chromosome | 22q12.1 |
| Function | is a major signaling cascade activated by cellular stress and pro-inflammatory cytokines. |
| Molecular Weight | 41 kDa |
| Pathways | MAPK, MAPK pathway |
| UniProt ID | [Q16643](https://www.uniprot.org/uniprot/Q16643) |
| GeneCards | MAPK11 |
| Human Protein Atlas | MAPK11 |
| Environmental stress | UV radiation, oxidative stress, hypoxia |
| Inflammatory cytokines | IL-1β, TNF-α, IL-6 |
| Growth factors | Some growth factor signaling pathways |
| Pathogen-associated molecules | LPS through TLR signaling |
| Microglial activation | Controls pro-inflammatory cytokine production |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, Neuroinflammation, Stroke |
| Known Drugs/Compounds | Losmapimod |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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