| Gene Symbol | ELP1 |
| Full Name | Elongator Complex Subunit 1 |
| Chromosome | 6p21.31 |
| Function | Elongator Complex Subunit 1 (ELP1), also known as IKBKAP (IKK complex-associated protein), is a scaffolding protein that is part of the Elongator complex |
| Molecular Weight | ~140 kDa |
| Amino Acids | 238 aa |
| GeneCards | ELP1 |
| Human Protein Atlas | ELP1 |
| Transcription elongation | Elongator facilitates RNA polymerase II transcription through chromatin |
| Histone acetylation | The complex has histone acetyltransferase (HAT) activity, primarily through ELP3 |
| tRNA modification | Elongator modifies uridine at wobble positions in tRNAs (uridine 34), affecting translation accuracy |
| Cytoskeletal organization | ELP1 is involved in actin cytoskeleton dynamics |
| Neuronal function | Elongator is particularly important in neurons, affecting dendritic arborization and axon guidance |
| Associated Diseases | neurodegeneration |
| Interactions | Elongator |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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