gene 2,732 words KG: CLN7
Contents

CLN7 — Ceroid Lipofuscinosis, Neuronal 7 (MFSD8)

🧬 Gene Info
Gene SymbolCLN7
Full NameCeroid Lipofuscinosis, Neuronal 7
AliasesLINCL
Chromosome4q28.2
Protein TypeTransporter
Functionis a human gene that encodes a lysosomal membrane protein functioning as a putative transporter.
Primary ExpressionBrain, retina, liver, kidney, lung
Amino Acids476 aa
UniProt IDQ8N5M4
NCBI Gene ID256281
Ensembl IDENSG00000167695
OMIM614804
GeneCardsCLN7
Human Protein AtlasCLN7
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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Related Hypotheses (17)

Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Membrane Cholesterol Gradient Modulators
Score: 0.71
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69
Ganglioside Rebalancing Therapy
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74

Related Analyses (3)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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