| Gene Symbol | AFG3L2 |
| Full Name | AFG3 ATPase Family Member 2 |
| Chromosome | 18p11.21 |
| Protein Type | Protease |
| Function | AFG3L2 encodes a mitochondrial matrix ATP-dependent metalloprotease that is part of the m-AAA protease complex |
| Subcellular Localization | **Primary**: Mitochondrial inner membrane |
| Molecular Weight | 79.5 kDa |
| Amino Acids | 684 aa |
| UniProt ID | [Q9H045](https://www.uniprot.org/uniprot/Q9H045) |
| Ensembl ID | ENSG00000135740 |
| OMIM | 607051 |
| GeneCards | AFG3L2 |
| Human Protein Atlas | AFG3L2 |
| AFG3L1 | Paralog in humans (forms heteromeric complexes with AFG3L2) |
| YME1L1 | Another mitochondrial AAA protease |
| Associated Diseases | Autosomal Recessive Ataxia |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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