| Gene Symbol | Complement |
| Chromosome | 19p13.3 |
| Multiplex immunoassays | Platforms such as Meso Scale Discovery (MSD) and Luminex allow simultaneous measurement of multiple complement components and cytokines, useful for profiling neuroinflammation[@lindblom2019]. |
| Western Blot | Enables detection of C3 cleavage products (C3a, C3b, C3c, C3d) to assess complement activation status. |
| Simoa (Single Molecule Array) | Ultra-sensitive technology enabling detection of C3a in blood at concentrations below traditional ELISA limits[@song2021]. |
| Mass Spectrometry | Targeted proteomics can quantify C3 fragments with high specificity and is increasingly used in research settings. |
| Associated Diseases | ALS, Aging, Als, Alzheimer, Amyotrophic Lateral Sclerosis |
| KG Connections | 1362 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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