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mechanism 3,734 words KG: cellular_senescence
Contents

Cellular Senescence in Neurodegeneration

⚙ Mechanism Info
Namecellular_senescence
Key Genes/ProteinsCDKN2A, IRF, mTOR, PGAM5
Related Diseasescardiac_aging, myocardial_ischemia
Related PathwaysSIRT6_deficiency
Linked Hypotheses3 hypotheses

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Related Hypotheses (2)

Closed-loop neuromodulation-inspired cytokine axis suppressi
Score: 0.53P2RY12 activation induces cellular senescence in cerebral VS
Score: 0.37

Knowledge Graph (7 edges)

IRF activates cellular_senescence
cellular_senescence contributes_to cardiac_aging
cellular_senescence contributes_to myocardial_ischemia
CDKN2A induces cellular_senescence
PGAM5 inhibits cellular_senescence
mTOR activates cellular_senescence
SIRT6_deficiency causes cellular_senescence

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