| Gene Symbol | YKL40 |
| Aliases | YKL-40 (N-terminal tyrosine, lysine, leucine, 40 kDa), HC-gp39, BRP-39 |
| Chromosome | 1q32.1 |
| Protein Family | Chitinase-like proteins (glycoside hydrolase family 18) |
| GeneCards | YKL40 |
| Human Protein Atlas | YKL40 |
| Gene | CHI3L1 located on chromosome 1q32.1 |
| Protein | 383 amino acids, ~40 kDa |
| Diagnostic utility | Elevated in AD vs. controls (AUC ~0.75-0.85) |
| Disease progression | Levels correlate with cognitive decline |
| Amyloid correlation | Modest positive correlation with amyloid burden |
| Tau correlation | Some studies show association with tau pathology |
| Associated Diseases | Alzheimer's disease |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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