| Gene Symbol | CSF |
| Sensitivity | 80-95% in confirmed CJD cases |
| Specificity | 85-95% compared to other rapidly progressive dementias |
| Positive Predictive Value | High in clinically probable CJD |
| Negative Predictive Value | Moderate (a negative result does not rule out CJD) |
| Amyotrophic Lateral Sclerosis (ALS) | Correlates with disease progression |
| Guillain-Barré Syndrome | During acute phase |
| Multiple Sclerosis | During relapses |
| Brain Tumors | With necrosis |
| Stroke | Ischemic events |
| Associated Diseases | MULTIPLE SCLEROSIS |
| Known Drugs/Compounds | ADUCANUMAB |
| KG Connections | 134 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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