protein 749 words KG: BAG6
Contents

BAG6 Protein

🔬 Protein Info
Gene SymbolBAG6
Full NameBCL2-associated athanogene 6
Chromosome6p21.1
Protein TypeChaperone
FunctionIt operates in multiple cellular compartments including the cytosol, nucleus, and endoplasmic reticulum.
Molecular Weight326 kDa
UniProt IDQ9Y5W5
NCBI Gene ID10127
Ensembl IDENSG00000138193
OMIM607186
GeneCardsBAG6
Human Protein AtlasBAG6
N-terminal DomainContains multiple LGL (Leu-Gly-Phe-Asn) sequence repeats that mediate client protein recognition
BAG DomainC-terminal BAG domain (~50 aa) functions as the Hsp70 nucleotide exchange factor
UBA DomainUbiquitin-associated domain for recruiting ubiquitinated substrates
Associated Diseasesneurodegeneration
InteractionsALS, UBQLN2
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph (12 edges)

BAG6 activates UBQLN2
BAG6 inhibits UBQLN2
BAG6 implicated_in UBQLN2
BAG6 interacts_with UBQLN2
BAG6 associated_with Cg27014438
Cg27014438 regulates BAG6
Rs28732154 associated_with BAG6
proteins-bag6-protein describes BAG6
ALS associated_with BAG6
BAG6 participates_in oxidative stress response

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