| Gene Symbol | ADCY8 |
| Full Name | Adenylate Cyclase 8 |
| Chromosome | 8q24.22 |
| Function | ADCY8 plays essential roles in neuronal physiology: |
| Molecular Weight | 125 kDa |
| Exons | 28 |
| GeneCards | ADCY8 |
| Human Protein Atlas | ADCY8 |
| N-terminal extracellular domain | Contains glycosylation sites |
| Transmembrane region (M1-M6) | Forms the membrane-spanning core |
| Calmodulin-binding domain | Located in the C-terminal cytoplasmic region |
| Cerebral cortex | Layer-specific expression in pyramidal neurons |
| Cerebellum | Enriched in Purkinje cells |
| Associated Diseases | long_term_spatial_memory_formation, migratory distance |
| Interactions | PKA |
| SciDEX Hypotheses | Circadian-Spatial Memory Coupling Therapy Epigenetic ADCY8 Memory Programming Hippocampal ADCY8 Upregulation for Alzheimer's Nav (+4 more) |
| KG Connections | 33 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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