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Debates

883 items
IdQuestionQuality ScoreNum Hypotheses GeneratedNum RoundsStatusCreated AtAnalysis Id
sess_sda-2026-04-01-SPMs (resolvins, protectins, maresins) from omega-3s may promote inflammation re0.8374completed2026-04-07sda-2026-04-01-gap-014
sess_sda-2026-04-01-Analysis question not specified0.8174completed2026-04-07sda-2026-04-01-gap-20260401231108
sess_sda-2026-04-01-Analysis question not specified0.5314completed2026-04-07sda-2026-04-01-gap-9137255b
sess_sda-2026-04-01-Can gut-brain axis modulation prevent or slow Alzheimer's disease pathology?0.9574completed2026-04-07sda-2026-04-01-003
sess_sda-2026-04-01-How to break the GBA-alpha-synuclein bidirectional loop for Parkinson's Disease 0.9074completed2026-04-07sda-2026-04-01-002
sess_sda-2026-04-01-What are the most promising therapeutic strategies for targeting TREM2 in Alzhei0.9574completed2026-04-07sda-2026-04-01-001
sess_sda-2026-04-01-Analysis question not specified0.8734completed2026-04-07sda-2026-04-01-gap-auto-fd6b1635d9
sess_sda-2026-04-01-Sleep disruption as cause and consequence of neurodegeneration0.9174completed2026-04-07sda-2026-04-01-gap-v2-18cf98ca
sess_sda-2026-04-01-RNA binding protein dysregulation across ALS FTD and AD0.8874completed2026-04-07sda-2026-04-01-gap-v2-68d9c9c1
sess_sda-2026-04-01-Synaptic pruning by microglia in early AD0.9574completed2026-04-07sda-2026-04-01-gap-v2-691b42f1
sess_sda-2026-04-01-Mitochondrial transfer between astrocytes and neurons0.9574completed2026-04-07sda-2026-04-01-gap-v2-89432b95
sess_sda-2026-04-01-Epigenetic clocks and biological aging in neurodegeneration0.9374completed2026-04-07sda-2026-04-01-gap-v2-bc5f270e
sess_sda-2026-04-01-Perivascular spaces and glymphatic clearance failure in AD0.9574completed2026-04-07sda-2026-04-01-gap-v2-ee5a5023
sess_sda-2026-04-01-What are the mechanisms by which gut microbiome dysbiosis influences Parkinson's0.9574completed2026-04-07sda-2026-04-01-gap-20260401-225149
sess_SDA-2026-04-06-TREM2 Therapeutic Strategy Post-INVOKE-20.9374completed2026-04-06SDA-2026-04-06-gap-001
sess_SDA-2026-04-04-Neuroinflammation and microglial priming in early AD0.9573completed2026-04-04SDA-2026-04-04-gap-neuroinflammation-microglial-20260404
sess_SDA-2026-04-04-Neuroinflammation and microglial priming in early Alzheimer's Disease0.9573completed2026-04-04SDA-2026-04-04-gap-neuro-microglia-early-ad-20260404
sess_SDA-2026-04-04-Tau propagation mechanisms and therapeutic interception points0.9573completed2026-04-04SDA-2026-04-04-gap-tau-prop-20260402003221
sess_SDA-2026-04-04-Senescent cell clearance as neurodegeneration therapy0.9573completed2026-04-04SDA-2026-04-04-gap-senescent-clearance-neuro
sess_analysis_sea_adWhat are the cell-type specific vulnerability mechanisms in Alzheimer's disease 0.6804completed2026-04-04analysis_sea_ad_001
sess_SDA-2026-04-04-SEA-AD Single-Cell Analysis: Cell-Type Vulnerability in Alzheimer's Disease0.8854completed2026-04-04SDA-2026-04-04-analysis_sea_ad_001
sess_SDA-2026-04-04-Which metabolic biomarkers can distinguish therapeutic response from disease pro0.9274completed2026-04-04SDA-2026-04-04-gap-debate-20260403-222618-c698b06a
sess_SDA-2026-04-04-How do neurodegeneration gene expression patterns in SEA-AD differ from other po0.9474completed2026-04-04SDA-2026-04-04-gap-debate-20260403-222549-20260402
sess_SDA-2026-04-04-How do astrocyte-neuron metabolic interactions change during disease progression0.9374completed2026-04-04SDA-2026-04-04-gap-debate-20260403-222618-e6a431dd
sess_SDA-2026-04-03-The debate mentioned gene expression profiling but did not specify which neural 0.9374completed2026-04-04SDA-2026-04-03-gap-debate-20260403-222543-20260402
sess_SDA-2026-04-03-While ketone metabolism was discussed as therapeutic, the debate revealed no cle0.8084completed2026-04-04SDA-2026-04-03-gap-debate-20260403-222618-2709aad9
sess_SDA-2026-04-03-The debate highlighted TFEB's role in mitochondrial-lysosomal coupling but could0.9574completed2026-04-04SDA-2026-04-03-gap-debate-20260403-222617-8eb5bdbc
sess_SDA-2026-04-03-What gene expression changes in the aging mouse brain predict neurodegenerative 0.9574completed2026-04-04SDA-2026-04-03-gap-aging-mouse-brain-v3-20260402
sess_SDA-2026-04-03-What gene expression changes in the aging mouse brain predict neurodegenerative 0.9564completed2026-04-04SDA-2026-04-03-gap-aging-mouse-brain-v2-20260402
sess_SDA-2026-04-03-What gene expression changes in the aging mouse brain predict neurodegenerative 0.9564completed2026-04-04SDA-2026-04-03-gap-aging-mouse-brain-20260402
sess_SDA-2026-04-03-Evaluate the potential of CRISPR/Cas9 and related gene editing technologies for 0.9574completed2026-04-04SDA-2026-04-03-gap-crispr-neurodegeneration-20260402
sess_SDA-2026-04-03-Comprehensive analysis of immune cell subtypes in neurodegeneration: microglia s0.8574completed2026-04-04SDA-2026-04-03-gap-immune-atlas-neuroinflam-20260402
sess_SDA-2026-04-03-What cell types are most vulnerable in Alzheimers Disease based on SEA-AD transc0.9274completed2026-04-04SDA-2026-04-03-gap-seaad-20260402025452
sess_SDA-2026-04-03-Analyze circuit-level changes in neurodegeneration using Allen Institute Neural 0.9564completed2026-04-04SDA-2026-04-03-26abc5e5f9f2
sess_SDA-2026-04-03-Investigate prion-like spreading of tau pathology through connected brain region0.9574completed2026-04-04SDA-2026-04-03-gap-tau-prop-20260402003221
sess_SDA-2026-04-03-What cell types are most vulnerable in Alzheimers Disease based on SEA-AD transc0.9074completed2026-04-03SDA-2026-04-03-gap-seaad-v4-20260402065846
sess_SDA-2026-04-03-What cell types are most vulnerable in Alzheimers Disease based on SEA-AD transc0.9574completed2026-04-03SDA-2026-04-03-gap-seaad-v3-20260402063622
sess_SDA-2026-04-03-What cell types are most vulnerable in Alzheimer's Disease based on SEA-AD trans0.9564completed2026-04-03SDA-2026-04-03-gap-seaad-v2-20260402032945
sess_SDA-2026-04-02-What cell types are most vulnerable in Alzheimer's Disease based on SEA-AD trans0.9574completed2026-04-03SDA-2026-04-02-gap-seaad-v2-20260402032945
debate-seaad-2026040Cell-type specific expression patterns of neurodegeneration genes in SEA-AD0.6853completed2026-04-02analysis-SEAAD-20260402
sess_SDA-2026-04-02-How does metabolic reprogramming (glucose metabolism shifts, brain insulin resis0.7334completed2026-04-02SDA-2026-04-02-gap-v2-5d0e3052
sess_SDA-2026-04-02-What gene expression changes in the aging mouse brain predict neurodegenerative 0.7144completed2026-04-02SDA-2026-04-02-gap-aging-mouse-brain-v5-20260402
sess_SDA-2026-04-02-What cell types are most vulnerable in Alzheimers Disease based on SEA-AD transc0.7434completed2026-04-02SDA-2026-04-02-gap-seaad-v4-20260402065846
sess_SDA-2026-04-02-Epigenetic reprogramming in aging neurons0.9574completed2026-04-02SDA-2026-04-02-gap-epigenetic-reprog-b685190e
sess_SDA-2026-04-02-Extracellular vesicle biomarkers for early AD detection0.8774completed2026-04-02SDA-2026-04-02-gap-ev-ad-biomarkers
sess_SDA-2026-04-02-Investigate prion-like spreading of tau pathology through connected brain region0.8864completed2026-04-02SDA-2026-04-02-gap-tau-prop-20260402003221
sess_SDA-2026-04-02-What cell types are most vulnerable in Alzheimers Disease based on SEA-AD transc0.5704completed2026-04-02SDA-2026-04-02-gap-seaad-v3-20260402063622
sess_SDA-2026-04-02-Senescent cell clearance as neurodegeneration therapy0.9574completed2026-04-02SDA-2026-04-02-gap-senescent-clearance-neuro
sess_SDA-2026-04-02-Evaluate the potential of CRISPR/Cas9 and related gene editing technologies for 0.9074completed2026-04-02SDA-2026-04-02-gap-crispr-neurodegeneration-20260402
sess_SDA-2026-04-02-The disease-associated microglia (DAM) phenotype involves TREM2 upregulation, bu0.8974completed2026-04-02SDA-2026-04-02-gap-001
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