Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about stress granule assembly: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Senescence | associated_with | process | 0.85 |
| CELL SURVIVAL | protects_against | entity | 0.85 |
| Tumorigenicity | regulates | phenotype | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| G3BP1 | regulates | entity | 0.95 |
| G3BP1 | mediates | protein | 0.92 |
| Genetic Mutations | associated_with | variant | 0.90 |
| 41067892 | is critical for | paper | 0.90 |
| Stress Granules | component_of | process | 0.90 |
| Prrc2A | regulates | protein | 0.88 |
| Prrc2B | regulates | protein | 0.88 |
| Prrc2C | regulates | protein | 0.88 |
| genetic mutations | inhibits | phenotype | 0.85 |
| G3BP1 | regulates | gene | 0.70 |
| 23092511 | is a contributing factor in | paper | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| TIA1 Low-Complexity Domain Oxidation Drives Aberrant Stress | 0.810 | ALS | - |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-06 | 7 hypotheses Top: 0.700
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning stress granule assembly in their description or question text
No additional research found