Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about signaling pathways: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| neurodegeneration | implicated_in | disease | 0.80 |
| Autophagy | regulates | process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Mitochondria | regulates | cell_type | 0.90 |
| Primary Cilia | regulates | cell_type | 0.90 |
| HDAC3 | modulates | gene | 0.85 |
| MAP6 | contributes_to | protein | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neuroinflammation | 2026-04-15 | 7 hypotheses Top: 0.752
neurodegeneration | 2026-04-06 | 7 hypotheses Top: 0.618
neuroinflammation | 2026-04-06 | 7 hypotheses Top: 0.740
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.70 · 2026-04-22
closed · Rounds: 4 · Score: 0.67 · 2026-04-22
closed · Rounds: 5 · Score: 0.95 · 2026-04-15
Hypotheses and analyses mentioning signaling pathways in their description or question text
No additional research found