cell_type

Primary Cilia

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Primary Cilia: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

13Outgoing

2Incoming

0Experiments

0Debates

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🧫 Cell Type Info

Cell Type	Primary Cilia
Key Markers	SHH, MFN2
Key Pathways	Ciliary Signaling Pathways, Signaling Pathways
Associated Diseases	Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Stroke, brain disorders

Pathway Diagram

graph TD
    Primary_Cilia["Primary Cilia"] -->|"mediates"| Ciliary_Signaling_Pathways["Ciliary Signaling Pathways"]
    style Ciliary_Signaling_Pathways fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    Primary_Cilia["Primary Cilia"] -->|"expressed in"| NEURON["NEURON"]
    style NEURON fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Primary_Cilia["Primary Cilia"] -->|"expressed in"| ASTROCYTES["ASTROCYTES"]
    style ASTROCYTES fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Primary_Cilia["Primary Cilia"] -->|"regulates"| Signaling_Pathways["Signaling Pathways"]
    style Signaling_Pathways fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    Primary_Cilia["Primary Cilia"] -->|"expressed in"| Neurons["Neurons"]
    style Neurons fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Primary_Cilia["Primary Cilia"] -->|"regulates"| NEURODEGENERATION["NEURODEGENERATION"]
    style NEURODEGENERATION fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    Primary_Cilia["Primary Cilia"] -->|"involved in"| Alzheimer_s_Disease["Alzheimer's Disease"]
    style Alzheimer_s_Disease fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    SHH["SHH"] -->|"binds"| Primary_Cilia["Primary Cilia"]
    style SHH fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    style Primary_Cilia fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (13)

Target	Relation	Type	Str
Ciliary Signaling Pathways	mediates	pathway	0.90
Signaling Pathways	regulates	pathway	0.90
ASTROCYTES	expressed_in	cell_type	0.90
NEURON	expressed_in	cell_type	0.90
Neurons	expressed_in	cell_type	0.85
Astrocytes	expressed_in	cell_type	0.85
NEURODEGENERATION	regulates	process	0.85
Aging	involved_in	process	0.70
Parkinson's Disease	involved_in	disease	0.70
Stroke	involved_in	disease	0.70
Amyotrophic Lateral Sclerosis	involved_in	disease	0.70
Alzheimer's Disease	involved_in	disease	0.70
brain disorders	regulates	disease	0.70

Incoming (2)

Source	Relation	Type	Str
SHH	binds	protein	0.85
SHH	interacts_with	protein	0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning Primary Cilia in their description or question text

No additional research found