Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about niacin: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Triglycerides | downregulates | biomarker | 0.95 |
| Hdl Cholesterol | upregulates | biomarker | 0.95 |
| NADP+ | associated_with | compound | 0.95 |
| NAD+ depletion | inhibits | mechanism | 0.95 |
| Pellagra | protects_against | disease | 0.90 |
| Atherosclerosis | protects_against | disease | 0.90 |
| ADIPOQ | upregulates | gene | 0.85 |
| mitochondrial biogenesis | activates | mechanism | 0.80 |
| Migraine | treats | disease | 0.75 |
| Hepatoma | inhibits | disease | 0.75 |
| Hyperphosphatemia | treats | disease | 0.75 |
| Type 1 Diabetes | protects_against | disease | 0.70 |
| GPR109A | activates | protein | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| 35320002 | serves as | paper | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning niacin in their description or question text
No additional research found