Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MULTIPLE MYELOMA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MULTIPLE MYELOMA |
graph TD
MULTIPLE_MYELOMA[MULTIPLE MYELOMA]
IRF4_Inhibition[IRF4 Inhibition] -->|targets| MULTIPLE_MYELOMA
PI3K_AKT_mTOR[PI3K/AKT/mTOR] -->|activates| MULTIPLE_MYELOMA
IRF4[IRF4] -->|target for| MULTIPLE_MYELOMA
IRF4_Regulatory_Network[IRF4 Regulatory Network] -->|involved_in| MULTIPLE_MYELOMA
PI3K[PI3K] -->|target for| MULTIPLE_MYELOMA
RAS_MAPK[RAS/MAPK] -->|implicated in| MULTIPLE_MYELOMA
IRF4_inhibition[IRF4 inhibition] -->|suppresses| MULTIPLE_MYELOMA
IRF4_regulatory_network[IRF4 regulatory network] -->|drives| MULTIPLE_MYELOMA| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| IRF4 | associated_with | gene | 0.98 |
| IRF4 Inhibition | targets | mechanism | 0.96 |
| PI3K/AKT/mTOR | activates | pathway | 0.95 |
| IRF4 | therapeutic_target | protein | 0.95 |
| IRF4 Regulatory Network | involved_in | pathway | 0.94 |
| PI3K/AKT/mTOR | therapeutic_target | pathway | 0.92 |
| RAS/MAPK | implicated_in | pathway | 0.90 |
| PI3K | therapeutic_target | protein | 0.90 |
| PI3K/AKT/mTOR | implicated_in | pathway | 0.90 |
| IRF4 inhibition | suppresses | process | 0.90 |
| IRF4 regulatory network | drives | pathway | 0.90 |
| MTOR | therapeutic_target | gene | 0.88 |
| IRF4 Inhibition | treats | mechanism | 0.88 |
| MTOR | regulates | gene | 0.85 |
| HDAC inhibitors | treats | drug | 0.80 |
| IRF4 | required_for | gene | 0.80 |
| MTOR | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MULTIPLE MYELOMA in their description or question text
No additional research found