Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about cystatin C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| TREM2 | activates | protein | 0.70 |
| neuroinflammation | prevents | mechanism | 0.70 |
| complement cascade | modulates | pathway | 0.70 |
| amyloid plaques | reduces | phenotype | 0.70 |
| CSF inflammatory markers | associated_with | biomarker | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LRP1 | regulates | protein | 0.70 |
| cancer | causes | phenotype | 0.70 |
| systemic cancer | causes | phenotype | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Direct cystatin C inhibition of tau aggregation | 0.390 | neurodegeneration | Does the cancer-cystatin-C-TREM2 pathway |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-25 | 8 hypotheses Top: 0.640
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning cystatin C in their description or question text
No additional research found