Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about cellular aging: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| senescence | mediates | process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Senescence | involved_in | process | 0.95 |
| 27235538 | is one of the upstream causes of | paper | 0.90 |
| SQSTM1 | protects_against | gene | 0.90 |
| Epigenetic Reprogramming | modulates | process | 0.85 |
| Mitochondrial Health | modulates | phenotype | 0.82 |
| Proteostasis | regulates | process | 0.82 |
| Proteostasis | modulates | process | 0.75 |
| β-hydroxybutyrate | modulates | metabolite | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
metabolic neuroscience | 2026-04-03 | 7 hypotheses Top: 0.773
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning cellular aging in their description or question text
No additional research found