protein

XRCC4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about XRCC4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections

0Hypotheses

0Analyses

3Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for XRCC4 Protein

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🔬 Protein Info

Gene Symbol	XRCC4
Full Name	X-Ray Repair Cross Complementing 4
Chromosome	5q14.1
Function	The XRCC4 protein forms a stable heterotetramer with LIG4, which is required for
Primary Expression	certain tumors as an adaptive response
Molecular Weight	33 kDa
Amino Acids	336 aa
UniProt ID	[Q01426](https://www.uniprot.org/uniprot/Q01426)
Ensembl ID	ENSG00000152457
GeneCards	XRCC4
Human Protein Atlas	XRCC4
Associated Diseases	Cancer
KG Connections	6 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

XRCC4

gene · 911 words

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XRCC4 Protein

protein · 626 words

→

Pathway Diagram

flowchart TD
    XRCC4(["XRCC4"])
    Cancer["Cancer"]
    Protein_Folding["Protein Folding"]
    Dna_Repair["Dna Repair"]
    DNA(["DNA"])
    CANCER(["CANCER"])
    GENES(["GENES"])
    neurodegeneration["neurodegeneration"]

    XRCC4 -->|"causes"| Cancer
    XRCC4 -->|"causes"| Protein_Folding
    XRCC4 -->|"causes"| Dna_Repair
    DNA -->|"associated with"| XRCC4
    CANCER -->|"causes"| XRCC4
    GENES -->|"causes"| XRCC4
    XRCC4 -->|"implicated in"| neurodegeneration

    style XRCC4 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (3)

Target	Relation	Type	Str
Cancer	causes	disease	0.65
Protein Folding	causes	pathway	0.60
Dna Repair	causes	pathway	0.60

Incoming (3)

Source	Relation	Type	Str
DNA	associated_with	gene	0.60
CANCER	causes	gene	0.60
GENES	causes	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning XRCC4 in their description or question text

No additional research found