protein

USP10

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about USP10: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

6Outgoing

2Incoming

0Experiments

0Debates

Summary

USP10 is a member of the Ubiquitin Specific Peptidase (USP) family of deubiquitinating enzymes. It contains a conserved catalytic domain with the characteristic Cys, His, and Asp residues that form the catalytic triad.

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🔬 Protein Info

Gene Symbol	USP10
Function	USP10 is a member of the Ubiquitin Specific Peptidase (USP) family of deubiquitinating enzymes. It contains a conserved catalytic domain with the characteristic Cys, His, and Asp residues that form...
Subcellular Localization	and substrate specificity, and a C-terminal domain that contributes to protein-p
GeneCards	USP10
Human Protein Atlas	USP10
Associated Diseases	esophageal squamous cell carcinoma
Known Drugs/Compounds	FW-04-806, Spautin-1
KG Connections	8 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

DUSP10 Gene

gene · 1018 words

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USP10 Protein

protein · 648 words

→

Pathway Diagram

graph TD
    USP10["USP10"]
    UBIQUITIN["UBIQUITIN"]
    USP10 -->|"removes"| UBIQUITIN
    ANLN["ANLN"]
    USP10 -->|"deubiquitinates"| ANLN
    Spautin_1["Spautin-1"]
    Spautin_1 -->|"inhibits"| USP10
    cytokinesis["cytokinesis"]
    USP10 -->|"promotes"| cytokinesis
    FW_04_806["FW-04-806"]
    FW_04_806 -->|"inhibits"| USP10
    esophageal_squamous_cell_carcinoma["esophageal squamous cell carcinoma"]
    USP10 -->|"therapeutic_target"| esophageal_squamous_cell_carcinoma
    style USP10 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (6)

Target	Relation	Type	Str
UBIQUITIN	removes	protein	0.95
ANLN	deubiquitinates	protein	0.95
cytokinesis	promotes	process	0.90
DDX1	degrades	protein	0.85
esophageal squamous cell carcinoma	therapeutic_target	disease	0.85
PRMT1	associated_with	protein	0.80

Incoming (2)

Source	Relation	Type	Str
Spautin-1	inhibits	compound	0.95
FW-04-806	inhibits	drug	0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning USP10 in their description or question text

No additional research found