gene

sptbn4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about sptbn4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections

0Hypotheses

0Analyses

5Outgoing

4Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	SPTBN4
Full Name	Spectrin Beta Non-Erythrocytic 4 (βIV-Spectrin)
Chromosome	19q13.13
Function	is a specialized neuronal compartment located at the proximal axon that serves as the primary site of action potential initiation in most neurons.
Primary Expression	the nervous system as multiple splice isoforms, with the longest isoform (βIV-spectrin) containing:
Amino Acids	724 aa
UniProt ID	Q9H6G1
NCBI Gene ID	10529
Ensembl ID	ENSG00000197894
OMIM	607666
GeneCards	SPTBN4
Human Protein Atlas	SPTBN4
Databases	GeneCards HPA STRING

🔮 Predicted Structure: sptbn4 — AlphaFold Q9H6G1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

sptbn4

gene · 1690 words

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Pathway Diagram

flowchart TD
    N0["SPTBN4"]
    N1["Epilepsy"]
    N0 -->|"expressed in"| N1
    N2["Als"]
    N0 -->|"expressed in"| N2
    N3["Autism"]
    N0 -->|"expressed in"| N3
    N4["SPTBN2"]
    N4 -->|"associated with"| N0
    N5["GENES"]
    N5 -->|"associated with"| N0
    N6["neurodegeneration"]
    N0 -->|"implicated in"| N6

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 disease
    class N4 gene
    class N5 gene

Outgoing (5)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:SPTBN4	data_in	dataset_row	0.00
ds-83b31ef18d49	provides_data_for	dataset	1.00
Epilepsy	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
Autism	expressed_in	disease	0.65

Incoming (4)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:SPTBN4	data_in	dataset_row	0.00
ds-83b31ef18d49	data_in	dataset	1.00
GENES	associated_with	gene	0.60
SPTBN2	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning sptbn4 in their description or question text

No additional research found