Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC38A9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
SLC38A9[SLC38A9]
SLC38A9 -->|activates| MTOR[MTOR]
SLC38A9 -->|mediates| MTORC1[MTORC1]
SLC38A9 -->|mediates| mTORC1_signaling[mTORC1 signaling]
SLC38A9 -->|interacts| NPC1[NPC1]
SLC38A9 -->|involved_in| Cholesterol_Sensing[Cholesterol Sensing]
SLC38A9 -->|expressed in| Lysosomal_Membrane[Lysosomal Membrane]
SLC38A9 -->|mediates| Lysosomal_Recruitment[Lysosomal Recruitment]
SLC38A9 -->|involved_in| Nutrient_Sensing[Nutrient Sensing]
SLC38A9 -->|involved_in| cholesterol_responsive_signali[cholesterol-responsive signaling]
NPC1 -->|binds| SLC38A9
MTOR -->|interacts| SLC38A9| Target | Relation | Type | Str |
|---|---|---|---|
| MTORC1 | activates | protein | 0.95 |
| MTOR | activates | protein | 0.95 |
| MTORC1 | mediates | protein | 0.95 |
| mTORC1 signaling | mediates | pathway | 0.92 |
| Lysosomal Membrane | expressed_in | cell_type | 0.90 |
| Cholesterol Sensing | involved_in | process | 0.90 |
| NPC1 | interacts_with | protein | 0.90 |
| Nutrient Sensing | involved_in | process | 0.85 |
| MTORC1 | interacts_with | protein | 0.85 |
| cholesterol-responsive signaling | involved_in | pathway | 0.85 |
| Lysosomal Recruitment | mediates | process | 0.85 |
| Arginine Sensing | involved_in | process | 0.80 |
| Arginine Sensing | mediates | process | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SLC38A9 in their description or question text
No additional research found